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What’s more, the analgesics didn’t even work. In contrast, none of the control group ended up in the hospital. Nine were hospitalized-three with kidney failure after taking ibuprofen, four with gastrointestinal bleeding after taking aspirin, and two with heart attacks, also after aspirin ingestion. There was one study in particular that freaked everyone out: A study of thousands of marathon runners found that those taking over-the-counter pain killers before the race had five times the incidence of organ damage. However, scientific evidence for this approach is currently lacking, and athletes should be aware of the potential risks in using NSAIDs as a prophylactic agent,” which include gastrointestinal pain and bleeding, kidney damage, and liver damage. They aren’t only using it for inflammation, though, but also prophylactically “prior to athletic participation to prevent pain and inflammation before it occurs. You may recall that I’ve previously explored the use of spinach for athletic performance and recovery, attributed to its “anti-inflammatory effects.” Most athletes aren’t using spinach to beat back inflammation, though they use drugs, typically non steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, which is used by up to 95 percent of collegiate athletes and three quarters of kids playing high school football. There have been at least eight randomized, double-blind, placebo-controlled trials of ginger for pain.